To study the effect of high density lipoprotein on the levels of random blood sugar, body mass index, and age

Abstract

Type 2 Diabetes Mellitus (T2DM) is a disorder in which there is inefficient use of
insulin hormone, leads to build up of glucose in the blood and eventually ends up
with hyperglycemia. The aim of this study was to test the hypothesis of interrelationship of age, body mass index (BMI), random blood sugar (RBS), Total
Cholesterol (TC), Triacylglycerols (TAGs), High Density Lipoproteins cholesterol
(HDLc), and Ca in patients with T2DM and also to compare these levels with that of
healthy controls. Plasma glucose, serum TC, TAGs, HDLc, and Ca were estimated
according to the instructions given in the methods. BMI was significantly higher and
also the levels of RBS, TC and TAGs were significantly higher in T2DM patients
compared with healthy controls. In addition, total serum Ca level was significantly
higher in T2DM patients compared with healthy controls. No significant differences
were observed in age and HDLc levels in T2DM patients compared with healthy
controls. In the patient group positive correlation was observed between age and
TAGs, age and HDLc, RBS and TC, RBS and TAGs, RBS and HDLc. In the control
group, we found positive correlation between age and HDLc and a negative
correlation between BMI and serum Ca. The authors conclude from the study that
alterations in the study parameters in T2DM group are due to hyperglycemia,
deficient scavenging action of HDLc and increase in serum calcium. Therefore, in
patients with T2DM, any compensation mechanism may become insufficient